The research paper CSE Seminar Topics Free Download Bio Informatics talks about Bioinformatics and the role of software engineers in the emerging discipline. The research paper clearly elucidates that Bioinformatics is the application of computers in biological sciences.
It is concerned with capturing, storing, graphically displaying, modeling and ultimately distributing biological information. It is becoming an essential tool in molecular biology as genome projects generate vast quantities of data.
The relation between Computers and Biology: The research abstract draws an interesting relationship between biology and computers. It says that Bioinformatics is the symbolic relationship between computational and biological sciences.
The ability to sort and extricate genetic codes from a human genomic database of 3 billion base pairs of DNA in a meaningful way is perhaps the simplest form of Bioinformatics.
Moving on to another level, Bioinformatics is useful in mapping different people’s genomes and deriving differences in their genetic makeup through pattern recognition software. But that is the easiest part.
What is more complex is to decipher the genetic code itself to see what the differences in genetic makeup between different people translate into in terms of physiological traits. The paper elucidates the above-mentioned facts by giving experimental references.
Application: The research abstract explains Computational simulation of experimental biology which is an important application of Bioinformatics, which is referred to as “in silico” testing. This is perhaps an area that will expand in a prolific way, given the need to obtain a greater degree of predictability in animal and human clinical trials.
Drawbacks: The research paper identifies certain limitations it states that today, the use of computers to model such processes is limited by, and must be placed in the context of, the current limits of understanding of these central themes.
At the outset, it is important to recognize that the rules of protein folding are still not fully understood; it cannot be invariably said that a particular sequence or a fold has arisen by divergent or convergent evolution; and it cannot necessarily be diagnosed as protein function, given knowledge only of its sequence or of its structure, in isolation.
Conclusion:
The research paper concludes by quoting the strides made by Bioinformatics in various fields. DNA forensics, bio-archeology, risk assessment, application of microbial genomics etc.